Clinical and Transmission Dynamics Characteristics of 406 Children with Coronavirus Disease 2019 in China: A Review
Identifieur interne : 000620 ( 2020/Analysis ); précédent : 000619; suivant : 000621Clinical and Transmission Dynamics Characteristics of 406 Children with Coronavirus Disease 2019 in China: A Review
Auteurs : Yang Zhen-Dong [République populaire de Chine] ; Zhou Gao-Jun [République populaire de Chine] ; Jin Run-Ming [République populaire de Chine] ; Liu Zhi-Sheng [République populaire de Chine] ; Dong Zong-Qi [République populaire de Chine] ; Xie Xiong [République populaire de Chine] ; Song Guo-Wei [République populaire de Chine]Source :
- The Journal of Infection [ 0163-4453 ] ; 2020.
Abstract
This article analyzes the demographic, epidemiological, clinical, laboratory and CT image data of 406 children with COVID-19. The clustered incidence of children's families is a dynamic transmission feature. There are more children than adults with asymptomatic infections, with milder conditions, faster recovery, and a better prognosis. These characteristics are the clinical features of children with COVID-19. Only 55 of the 406 cases were tested by anal swab virus for nucleic acid, 45 of which were positive, accounting for 81.8% of stool samples. Some concealed morbidity characteristics also bring difficulties to the early identification, prevention and control of COVID-19. Efforts should be made to prevent children from becoming a hidden source of transmission in kindergartens, schools or families.
Url:
DOI: 10.1016/j.jinf.2020.04.030
PubMed: NONE
PubMed Central: 7187854
Affiliations:
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wicri:level="1"><nlm:aff id="aff0001">Department of Respiratory Allergy, Beijing Children's Hospital of Beijing, Beijing 102208, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Respiratory Allergy, Beijing Children's Hospital of Beijing, Beijing 102208</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Gao Jun, Zhou" sort="Gao Jun, Zhou" uniqKey="Gao Jun Z" first="Zhou" last="Gao-Jun">Zhou Gao-Jun</name><affiliation wicri:level="1"><nlm:aff id="aff0001">Department of Respiratory Allergy, Beijing Children's Hospital of Beijing, Beijing 102208, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Respiratory Allergy, Beijing Children's Hospital of Beijing, Beijing 102208</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Run Ming, Jin" sort="Run Ming, Jin" uniqKey="Run Ming J" first="Jin" last="Run-Ming">Jin Run-Ming</name><affiliation wicri:level="1"><nlm:aff id="aff0002">Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author><author><name sortKey="Zhi Sheng, Liu" sort="Zhi Sheng, Liu" uniqKey="Zhi Sheng L" first="Liu" last="Zhi-Sheng">Liu Zhi-Sheng</name><affiliation wicri:level="1"><nlm:aff id="aff0003">Children's Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430016, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Children's Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430016</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author><author><name sortKey="Zong Qi, Dong" sort="Zong Qi, Dong" uniqKey="Zong Qi D" first="Dong" last="Zong-Qi">Dong Zong-Qi</name><affiliation wicri:level="1"><nlm:aff id="aff0003">Children's Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430016, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Children's Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430016</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author><author><name sortKey="Xiong, Xie" sort="Xiong, Xie" uniqKey="Xiong X" first="Xie" last="Xiong">Xie Xiong</name><affiliation wicri:level="1"><nlm:aff id="aff0004">Department of Pediatrics, Gezhouba Central Hospital, Third Clinical Medical College of Three Gorges University, Yichang 443002, Hubei, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Pediatrics, Gezhouba Central Hospital, Third Clinical Medical College of Three Gorges University, Yichang 443002, Hubei</wicri:regionArea><wicri:noRegion>Hubei</wicri:noRegion></affiliation></author><author><name sortKey="Guo Wei, Song" sort="Guo Wei, Song" uniqKey="Guo Wei S" first="Song" last="Guo-Wei">Song Guo-Wei</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Department of Emergency, Children's Hospital, Capital Institute of Pediatrics, Beijing 100020, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Emergency, Children's Hospital, Capital Institute of Pediatrics, Beijing 100020</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author></analytic><series><title level="j">The Journal of Infection</title><idno type="ISSN">0163-4453</idno><idno type="eISSN">1532-2742</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Highlights</title><p><list list-type="simple" id="celist0001"><list-item id="celistitem0001"><label>•</label><p id="para0007">This article analyzes the demographic, epidemiological, clinical, laboratory and CT image data of 406 children with COVID-19.</p></list-item><list-item id="celistitem0002"><label>•</label><p id="para0008">The clustered incidence of children's families is a dynamic transmission feature. There are more children than adults with asymptomatic infections, with milder conditions, faster recovery, and a better prognosis. These characteristics are the clinical features of children with COVID-19.</p></list-item><list-item id="celistitem0003"><label>•</label><p id="para0009">Only 55 of the 406 cases were tested by anal swab virus for nucleic acid, 45 of which were positive, accounting for 81.8% of stool samples.</p></list-item><list-item id="celistitem0004"><label>•</label><p id="para0010">Some concealed morbidity characteristics also bring difficulties to the early identification, prevention and control of COVID-19.</p></list-item><list-item id="celistitem0005"><label>•</label><p id="para0011">Efforts should be made to prevent children from becoming a hidden source of transmission in kindergartens, schools or families.</p></list-item></list></p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Wang, S" uniqKey="Wang S">S. Wang</name></author><author><name sortKey="Guo, L" uniqKey="Guo L">L. Guo</name></author><author><name sortKey="Chen, L" uniqKey="Chen L">L. Chen</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name></author><author><name sortKey="Hu, B" uniqKey="Hu B">B. Hu</name></author><author><name sortKey="Hu, C" uniqKey="Hu C">C. Hu</name></author><author><name sortKey="Zhu, F" uniqKey="Zhu F">F. Zhu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huijing, M" uniqKey="Huijing M">M. Huijing</name></author><author><name sortKey="Jianbo, S" uniqKey="Jianbo S">S. Jianbo</name></author><author><name sortKey="Yongjiao, W" uniqKey="Yongjiao W">W. Yongjiao</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Yuehua, Zhang" uniqKey="Yuehua Z">Zhang Yuehua</name></author><author><name sortKey="Meifang, Xiao" uniqKey="Meifang X">Xiao Meifang</name></author><author><name sortKey="Jiachong, Wang" uniqKey="Jiachong W">Wang Jiachong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, J F" uniqKey="Chan J">J.F. Chan</name></author><author><name sortKey="Yuan, S" uniqKey="Yuan S">S. Yuan</name></author><author><name sortKey="Kok, K H" uniqKey="Kok K">K.H. Kok</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xiao, F" uniqKey="Xiao F">F. Xiao</name></author><author><name sortKey="Tang, M" uniqKey="Tang M">M. Tang</name></author><author><name sortKey="Zheng, X" uniqKey="Zheng X">X. Zheng</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y. Liu</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. Li</name></author><author><name sortKey="Shan, H" uniqKey="Shan H">H. Shan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tang, An" uniqKey="Tang A">An Tang</name></author><author><name sortKey="Tong, Zhen Dong" uniqKey="Tong Z">Zhen-dong Tong</name></author><author><name sortKey="Wang, Hong Ling" uniqKey="Wang H">Hong-ling Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, T" uniqKey="Zhang T">T. Zhang</name></author><author><name sortKey="Cui, X" uniqKey="Cui X">X. Cui</name></author><author><name sortKey="Zhao, X" uniqKey="Zhao X">X. Zhao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="He, Y" uniqKey="He Y">Y. He</name></author><author><name sortKey="Wang, Z" uniqKey="Wang Z">Z. Wang</name></author><author><name sortKey="Li, F" uniqKey="Li F">F. Li</name></author><author><name sortKey="Shi, Y" uniqKey="Shi Y">Y. Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhimin, Chen" uniqKey="Zhimin C">Chen Zhimin</name></author><author><name sortKey="Junfen, Fu" uniqKey="Junfen F">Fu Junfen</name></author><author><name sortKey="Qiang, Shu" uniqKey="Qiang S">Shu Qiang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gao, J" uniqKey="Gao J">J. Gao</name></author><author><name sortKey="Tian, Z" uniqKey="Tian Z">Z. Tian</name></author><author><name sortKey="Yang, X" uniqKey="Yang X">X. Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Holshue, M L" uniqKey="Holshue M">M.L. Holshue</name></author><author><name sortKey="Debolt, C" uniqKey="Debolt C">C. DeBolt</name></author><author><name sortKey="Lindquist, S" uniqKey="Lindquist S">S. Lindquist</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Feng, Fang" uniqKey="Feng F">Fang Feng</name></author><author><name sortKey="Xiaoping, Luo" uniqKey="Xiaoping L">Luo Xiaoping</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Russell, C D" uniqKey="Russell C">C.D. Russell</name></author><author><name sortKey="Millar, J E" uniqKey="Millar J">J.E. Millar</name></author><author><name sortKey="Baillie, J K" uniqKey="Baillie J">J.K. Baillie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, Long" uniqKey="Chen L">Long Chen</name></author><author><name sortKey="Xiong, Jing" uniqKey="Xiong J">Jing Xiong</name></author><author><name sortKey="Bao, Lei" uniqKey="Bao L">Lei Bao</name></author><author><name sortKey="Shi, Yuan" uniqKey="Shi Y">Yuan Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shen, C" uniqKey="Shen C">C. Shen</name></author><author><name sortKey="Wang, Z" uniqKey="Wang Z">Z. Wang</name></author><author><name sortKey="Zhao, F" uniqKey="Zhao F">F. Zhao</name></author></analytic></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country><region><li>Hubei</li></region><settlement><li>Pékin</li><li>Wuhan</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Zhen Dong, Yang" sort="Zhen Dong, Yang" uniqKey="Zhen Dong Y" first="Yang" last="Zhen-Dong">Yang Zhen-Dong</name></noRegion><name sortKey="Gao Jun, Zhou" sort="Gao Jun, Zhou" uniqKey="Gao Jun Z" first="Zhou" last="Gao-Jun">Zhou Gao-Jun</name><name sortKey="Guo Wei, Song" sort="Guo Wei, Song" uniqKey="Guo Wei S" first="Song" last="Guo-Wei">Song Guo-Wei</name><name sortKey="Run Ming, Jin" sort="Run Ming, Jin" uniqKey="Run Ming J" first="Jin" last="Run-Ming">Jin Run-Ming</name><name sortKey="Xiong, Xie" sort="Xiong, Xie" uniqKey="Xiong X" first="Xie" last="Xiong">Xie Xiong</name><name sortKey="Zhi Sheng, Liu" sort="Zhi Sheng, Liu" uniqKey="Zhi Sheng L" first="Liu" last="Zhi-Sheng">Liu Zhi-Sheng</name><name sortKey="Zong Qi, Dong" sort="Zong Qi, Dong" uniqKey="Zong Qi D" first="Dong" last="Zong-Qi">Dong Zong-Qi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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